Human SNP ID | rs10817408 |
---|---|
Human chromosome | chr9 |
Human SNP position | 112925455 |
Pig chromosome | chr1 |
Pig SNP position | 284426319 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 9q32 |
Chromosome id | chr9 |
Chromosome position | 112925455 |
Reported gene | NR |
Mapped gene | SLC46A2 - ZNF883 |
Upstream gene id | 57864 |
Downstream gene id | 169834 |
SNP gene ids | |
Upstream gene distance | 34513 |
Downstream gene distance | 71665 |
SNP risk allele | rs10817408-C |
SNPs | rs10817408 |
Merged | 0 |
SNP id current | 10817408 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.149460512683578 |
P value | 0.000007 |
Pvalue mlog | 5.15490195998574 |
P value text | (IGP40) |
Or beta | 0.2234 |
%95 Ci | [0.13-0.32] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 9q32 |
Chromosome id | chr9 |
Chromosome position | 112925455 |
Reported gene | NR |
Mapped gene | SLC46A2 - ZNF883 |
Upstream gene id | 57864 |
Downstream gene id | 169834 |
SNP gene ids | |
Upstream gene distance | 34513 |
Downstream gene distance | 71665 |
SNP risk allele | rs10817408-C |
SNPs | rs10817408 |
Merged | 0 |
SNP id current | 10817408 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.149316170753455 |
P value | 0.000006 |
Pvalue mlog | 5.22184874961635 |
P value text | (IGP69) |
Or beta | 0.2277 |
%95 Ci | [0.13-0.33] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 9q32 |
Chromosome id | chr9 |
Chromosome position | 112925455 |
Reported gene | NR |
Mapped gene | SLC46A2 - ZNF883 |
Upstream gene id | 57864 |
Downstream gene id | 169834 |
SNP gene ids | |
Upstream gene distance | 34513 |
Downstream gene distance | 71665 |
SNP risk allele | rs10817408-C |
SNPs | rs10817408 |
Merged | 0 |
SNP id current | 10817408 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.149506685242978 |
P value | 0.000006 |
Pvalue mlog | 5.22184874961635 |
P value text | (IGP75) |
Or beta | 0.2271 |
%95 Ci | [0.13-0.33] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |