SNP Detail For rs10817408
1.Mapping Information
Human SNP ID rs10817408
Human chromosome chr9
Human SNP position 112925455
Pig chromosome chr1
Pig SNP position 284426319
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region9q32
Chromosome idchr9
Chromosome position112925455
Reported geneNR
Mapped geneSLC46A2 - ZNF883
Upstream gene id57864
Downstream gene id169834
SNP gene ids
Upstream gene distance34513
Downstream gene distance71665
SNP risk allelers10817408-C
SNPsrs10817408
Merged0
SNP id current10817408
Contextintergenic_variant
Intergenic1
Allele frequency0.149460512683578
P value0.000007
Pvalue mlog5.15490195998574
P value text(IGP40)
Or beta0.2234
%95 Ci[0.13-0.32] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region9q32
Chromosome idchr9
Chromosome position112925455
Reported geneNR
Mapped geneSLC46A2 - ZNF883
Upstream gene id57864
Downstream gene id169834
SNP gene ids
Upstream gene distance34513
Downstream gene distance71665
SNP risk allelers10817408-C
SNPsrs10817408
Merged0
SNP id current10817408
Contextintergenic_variant
Intergenic1
Allele frequency0.149316170753455
P value0.000006
Pvalue mlog5.22184874961635
P value text(IGP69)
Or beta0.2277
%95 Ci[0.13-0.33] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region9q32
Chromosome idchr9
Chromosome position112925455
Reported geneNR
Mapped geneSLC46A2 - ZNF883
Upstream gene id57864
Downstream gene id169834
SNP gene ids
Upstream gene distance34513
Downstream gene distance71665
SNP risk allelers10817408-C
SNPsrs10817408
Merged0
SNP id current10817408
Contextintergenic_variant
Intergenic1
Allele frequency0.149506685242978
P value0.000006
Pvalue mlog5.22184874961635
P value text(IGP75)
Or beta0.2271
%95 Ci[0.13-0.33] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848