Human SNP ID | rs10813957 |
---|---|
Human chromosome | chr9 |
Human SNP position | 33153529 |
Pig chromosome | chr10 |
Pig SNP position | 37588237 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 9p21.1 |
Chromosome id | chr9 |
Chromosome position | 33153529 |
Reported gene | NR |
Mapped gene | B4GALT1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2683 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10813957-G |
SNPs | rs10813957 |
Merged | 0 |
SNP id current | 10813957 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.738414638629283 |
P value | 0.00000005 |
Pvalue mlog | 7.30102999566398 |
P value text | (IGP13) |
Or beta | 0.196 |
%95 Ci | [0.13-0.27] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 9p21.1 |
Chromosome id | chr9 |
Chromosome position | 33153529 |
Reported gene | NR |
Mapped gene | B4GALT1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2683 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10813957-G |
SNPs | rs10813957 |
Merged | 0 |
SNP id current | 10813957 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.738414638629283 |
P value | 0.000007 |
Pvalue mlog | 5.15490195998574 |
P value text | (IGP43) |
Or beta | 0.1601 |
%95 Ci | [0.09-0.23] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 9p21.1 |
Chromosome id | chr9 |
Chromosome position | 33153529 |
Reported gene | NR |
Mapped gene | B4GALT1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2683 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10813957-G |
SNPs | rs10813957 |
Merged | 0 |
SNP id current | 10813957 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.738414638629283 |
P value | 0.000000002 |
Pvalue mlog | 8.69897000433601 |
P value text | (IGP53) |
Or beta | 0.2163 |
%95 Ci | [0.15-0.29] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 9p21.1 |
Chromosome id | chr9 |
Chromosome position | 33153529 |
Reported gene | NR |
Mapped gene | B4GALT1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2683 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10813957-G |
SNPs | rs10813957 |
Merged | 0 |
SNP id current | 10813957 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.738414638629283 |
P value | 0.000000003 |
Pvalue mlog | 8.52287874528033 |
P value text | (IGP57) |
Or beta | 0.2125 |
%95 Ci | [0.14-0.28] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |