SNP Detail For rs10813957
1.Mapping Information
Human SNP ID rs10813957
Human chromosome chr9
Human SNP position 33153529
Pig chromosome chr10
Pig SNP position 37588237
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region9p21.1
Chromosome idchr9
Chromosome position33153529
Reported geneNR
Mapped geneB4GALT1
Upstream gene id
Downstream gene id
SNP gene ids2683
Upstream gene distance
Downstream gene distance
SNP risk allelers10813957-G
SNPsrs10813957
Merged0
SNP id current10813957
Contextintron_variant
Intergenic0
Allele frequency0.738414638629283
P value0.00000005
Pvalue mlog7.30102999566398
P value text(IGP13)
Or beta0.196
%95 Ci[0.13-0.27] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region9p21.1
Chromosome idchr9
Chromosome position33153529
Reported geneNR
Mapped geneB4GALT1
Upstream gene id
Downstream gene id
SNP gene ids2683
Upstream gene distance
Downstream gene distance
SNP risk allelers10813957-G
SNPsrs10813957
Merged0
SNP id current10813957
Contextintron_variant
Intergenic0
Allele frequency0.738414638629283
P value0.000007
Pvalue mlog5.15490195998574
P value text(IGP43)
Or beta0.1601
%95 Ci[0.09-0.23] unit decrease
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region9p21.1
Chromosome idchr9
Chromosome position33153529
Reported geneNR
Mapped geneB4GALT1
Upstream gene id
Downstream gene id
SNP gene ids2683
Upstream gene distance
Downstream gene distance
SNP risk allelers10813957-G
SNPsrs10813957
Merged0
SNP id current10813957
Contextintron_variant
Intergenic0
Allele frequency0.738414638629283
P value0.000000002
Pvalue mlog8.69897000433601
P value text(IGP53)
Or beta0.2163
%95 Ci[0.15-0.29] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region9p21.1
Chromosome idchr9
Chromosome position33153529
Reported geneNR
Mapped geneB4GALT1
Upstream gene id
Downstream gene id
SNP gene ids2683
Upstream gene distance
Downstream gene distance
SNP risk allelers10813957-G
SNPsrs10813957
Merged0
SNP id current10813957
Contextintron_variant
Intergenic0
Allele frequency0.738414638629283
P value0.000000003
Pvalue mlog8.52287874528033
P value text(IGP57)
Or beta0.2125
%95 Ci[0.14-0.28] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848