Human SNP ID | rs10792832 |
---|---|
Human chromosome | chr11 |
Human SNP position | 86156833 |
Pig chromosome | chr9 |
Pig SNP position | 22265308 |
PubMed ID | 24162737 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24162737 |
Study | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer__s disease. |
Disease/Trait | Alzheimer__s disease (late onset) |
Initial sample | 17,008 European ancestry cases, 37,154 European ancestry controls |
Replication sample | 8,572 European ancestry cases, 11,312 European ancestry controls |
Region | 11q14.2 |
Chromosome id | chr11 |
Chromosome position | 86156833 |
Reported gene | PICALM |
Mapped gene | PICALM - FNTAP1 |
Upstream gene id | 8301 |
Downstream gene id | 283226 |
SNP gene ids | |
Upstream gene distance | 86952 |
Downstream gene distance | 38298 |
SNP risk allele | rs10792832-G |
SNPs | rs10792832 |
Merged | 0 |
SNP id current | 10792832 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.642 |
P value | 9E-26 |
Pvalue mlog | 25.0457574905606 |
P value text | |
Or beta | 1.1494 |
%95 Ci | [1.12-1.18] |
Platform | Illumina [7055881] (imputed) |
CNV | N |
Mapped trait | Alzheimers disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000249 |
Study accession | GCST002245 |
PubMed ID | 25778476 |
Journal | Mol Psychiatry |
Link | www.ncbi.nlm.nih.gov/pubmed/25778476 |
Study | A novel Alzheimer disease locus located near the gene encoding tau protein. |
Disease/Trait | Alzheimer__s disease in APOE e4+ carriers |
Initial sample | 10,352 cases, 9,207 controls |
Replication sample | 1,250 European ancestry cases, 536 European ancestry controls |
Region | 11q14.2 |
Chromosome id | chr11 |
Chromosome position | 86156833 |
Reported gene | PICALM |
Mapped gene | PICALM - FNTAP1 |
Upstream gene id | 8301 |
Downstream gene id | 283226 |
SNP gene ids | |
Upstream gene distance | 86952 |
Downstream gene distance | 38298 |
SNP risk allele | rs10792832-G |
SNPs | rs10792832 |
Merged | 0 |
SNP id current | 10792832 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.65 |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | |
Or beta | 1.14 |
%95 Ci | [1.08-1.19] |
Platform | NR [NR] |
CNV | N |
Mapped trait | Alzheimers disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000249 |
Study accession | GCST002813 |