SNP Detail For rs10788575
1.Mapping Information
Human SNP ID rs10788575
Human chromosome chr10
Human SNP position 88008827
Pig chromosome chr14
Pig SNP position 109033030
2.Annotation Information
PubMed ID24509480
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24509480
StudyGenome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Disease/TraitType 2 diabetes
Initial sample12,171 European ancestry cases, 56,862 European ancestry controls, 6,952 East Asian ancestry cases, 11,865 East Asian ancestry controls, 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls, 1,804 Mexican ancestry cases, 779 Mexican ance
Replication sample21,491 European ancestry cases, 55,647 European ancestry controls
Region10q23.31
Chromosome idchr10
Chromosome position88008827
Reported genePTEN
Mapped genePTEN - LOC105378414
Upstream gene id5728
Downstream gene id105378414
SNP gene ids
Upstream gene distance36897
Downstream gene distance33491
SNP risk allelers10788575-A
SNPsrs10788575
Merged0
SNP id current10788575
Contextintergenic_variant
Intergenic1
Allele frequency
P value0.000009
Pvalue mlog5.04575749056067
P value text
Or beta1.06
%95 Ci[1.03-1.08]
PlatformAffymetrix, Illumina [2500000] (imputed)
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST002352