SNP Detail For rs1077835
1.Mapping Information
Human SNP ID rs1077835
Human chromosome chr15
Human SNP position 58431227
Pig chromosome chr1
Pig SNP position 125668449
2.Annotation Information
PubMed ID23505323
JournalJ Med Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23505323
StudyGenomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.
Disease/TraitHDL cholesterol
Initial sample1,122 Mexican ancestry hypertriglyceridemia cases, 1,118 Mexican ancestry controls
Replication sample1,067 Mexican ancestry hypertriglyceridemia cases, 1,054 Mexican ancestry controls
Region15q21.3
Chromosome idchr15
Chromosome position58431227
Reported geneLIPC
Mapped geneLIPC, LOC102724766
Upstream gene id
Downstream gene id
SNP gene ids3990, 102724766
Upstream gene distance
Downstream gene distance
SNP risk allelers1077835-A
SNPsrs1077835
Merged0
SNP id current1077835
Contextintron_variant
Intergenic0
Allele frequency0.38
P value0.00000000000002
Pvalue mlog13.698970004336
P value text
Or beta0.17
%95 Ci[0.13-0.21] unit decrease
PlatformIllumina [1361436] (imputed)
CNVN
Mapped traithigh density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004612
Study accessionGCST001904
PubMed ID25961943
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25961943
StudyThe impact of low-frequency and rare variants on lipid levels.
Disease/TraitTriglycerides
Initial sampleup to 62,166 European ancestry individuals
Replication sampleNA
Region15q21.3
Chromosome idchr15
Chromosome position58431227
Reported geneLIPC
Mapped geneLIPC, LOC102724766
Upstream gene id
Downstream gene id
SNP gene ids3990, 102724766
Upstream gene distance
Downstream gene distance
SNP risk allelers1077835-G
SNPsrs1077835
Merged0
SNP id current1077835
Contextintron_variant
Intergenic0
Allele frequency0.22
P value0.00000000000002
Pvalue mlog13.698970004336
P value text
Or beta0.059
%95 Ci[0.043-0.075] s.d. increase
PlatformAffymetrix, Illumina, Perlegen [up to 9657952] (imputed)
CNVN
Mapped traittriglyceride measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004530
Study accessionGCST002897