Human SNP ID | rs1077835 |
---|---|
Human chromosome | chr15 |
Human SNP position | 58431227 |
Pig chromosome | chr1 |
Pig SNP position | 125668449 |
PubMed ID | 23505323 |
---|---|
Journal | J Med Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23505323 |
Study | Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci. |
Disease/Trait | HDL cholesterol |
Initial sample | 1,122 Mexican ancestry hypertriglyceridemia cases, 1,118 Mexican ancestry controls |
Replication sample | 1,067 Mexican ancestry hypertriglyceridemia cases, 1,054 Mexican ancestry controls |
Region | 15q21.3 |
Chromosome id | chr15 |
Chromosome position | 58431227 |
Reported gene | LIPC |
Mapped gene | LIPC, LOC102724766 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3990, 102724766 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1077835-A |
SNPs | rs1077835 |
Merged | 0 |
SNP id current | 1077835 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.38 |
P value | 0.00000000000002 |
Pvalue mlog | 13.698970004336 |
P value text | |
Or beta | 0.17 |
%95 Ci | [0.13-0.21] unit decrease |
Platform | Illumina [1361436] (imputed) |
CNV | N |
Mapped trait | high density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004612 |
Study accession | GCST001904 |
PubMed ID | 25961943 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25961943 |
Study | The impact of low-frequency and rare variants on lipid levels. |
Disease/Trait | Triglycerides |
Initial sample | up to 62,166 European ancestry individuals |
Replication sample | NA |
Region | 15q21.3 |
Chromosome id | chr15 |
Chromosome position | 58431227 |
Reported gene | LIPC |
Mapped gene | LIPC, LOC102724766 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3990, 102724766 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1077835-G |
SNPs | rs1077835 |
Merged | 0 |
SNP id current | 1077835 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.22 |
P value | 0.00000000000002 |
Pvalue mlog | 13.698970004336 |
P value text | |
Or beta | 0.059 |
%95 Ci | [0.043-0.075] s.d. increase |
Platform | Affymetrix, Illumina, Perlegen [up to 9657952] (imputed) |
CNV | N |
Mapped trait | triglyceride measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004530 |
Study accession | GCST002897 |