SNP Detail For rs10774624
1.Mapping Information
Human SNP ID rs10774624
Human chromosome chr12
Human SNP position 111395984
Pig chromosome chr14
Pig SNP position 34607902
2.Annotation Information
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region12q24.12
Chromosome idchr12
Chromosome position111395984
Reported geneSH2B3, PTPN11
Mapped geneFAM109A - LOC105369984
Upstream gene id144717
Downstream gene id105369984
SNP gene ids
Upstream gene distance26863
Downstream gene distance846
SNP risk allelers10774624-G
SNPsrs10774624
Merged0
SNP id current10774624
Contextintron_variant
Intergenic1
Allele frequency0.5
P value0.000000007
Pvalue mlog8.15490195998574
P value text(EA)
Or beta1.09
%95 Ci[1.06-1.13]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318