Human SNP ID | rs10748128 |
---|---|
Human chromosome | chr12 |
Human SNP position | 69433878 |
Pig chromosome | chr5 |
Pig SNP position | 36288811 |
PubMed ID | 20881960 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20881960 |
Study | Hundreds of variants clustered in genomic loci and biological pathways affect human height. |
Disease/Trait | Height |
Initial sample | 133,653 European ancestry individuals |
Replication sample | 50,074 European ancestry individuals |
Region | 12q15 |
Chromosome id | chr12 |
Chromosome position | 69433878 |
Reported gene | FRS2 |
Mapped gene | LOC105369822 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105369822 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10748128-T |
SNPs | rs10748128 |
Merged | 0 |
SNP id current | 10748128 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.35 |
P value | 2E-20 |
Pvalue mlog | 19.698970004336 |
P value text | |
Or beta | 0.038 |
%95 Ci | [NR] unit increase |
Platform | Affymetrix, Illumina [2834208] (imputed) |
CNV | N |
Mapped trait | body height |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004339 |
Study accession | GCST000817 |
PubMed ID | 23563607 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23563607 |
Study | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. |
Disease/Trait | Height |
Initial sample | 8,097 European ancestry tall individuals, 8,099 European ancestry short individuals |
Replication sample | 4,872 European ancestry tall individuals, 4,831 European ancestry short individuals |
Region | 12q15 |
Chromosome id | chr12 |
Chromosome position | 69433878 |
Reported gene | FRS2 |
Mapped gene | LOC105369822 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105369822 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10748128-T |
SNPs | rs10748128 |
Merged | 0 |
SNP id current | 10748128 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.35 |
P value | 0.000000000000007 |
Pvalue mlog | 14.1549019599857 |
P value text | |
Or beta | 1.19 |
%95 Ci | [NR] |
Platform | Affymetrix, Illumina [~ 2800000] (imputed) |
CNV | N |
Mapped trait | body height |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004339 |
Study accession | GCST001956 |
PubMed ID | 25429064 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25429064 |
Study | Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. |
Disease/Trait | Height |
Initial sample | 36,227 East Asian ancestry individuals |
Replication sample | 57,699 East Asian ancestry individuals |
Region | 12q15 |
Chromosome id | chr12 |
Chromosome position | 69433878 |
Reported gene | FRS2 |
Mapped gene | LOC105369822 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105369822 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10748128-T |
SNPs | rs10748128 |
Merged | 0 |
SNP id current | 10748128 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.63 |
P value | 0.0000007 |
Pvalue mlog | 6.15490195998574 |
P value text | |
Or beta | 0.029 |
%95 Ci | [0.015-0.043] unit increase |
Platform | Affymetrix, Illumina [2704730] (imputed) |
CNV | N |
Mapped trait | body height |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004339 |
Study accession | GCST002702 |
PubMed ID | 25282103 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25282103 |
Study | Defining the role of common variation in the genomic and biological architecture of adult human height. |
Disease/Trait | Height |
Initial sample | 253,288 European ancestry individuals |
Replication sample | 80,067 European ancestry individuals |
Region | 12q15 |
Chromosome id | chr12 |
Chromosome position | 69433878 |
Reported gene | FRS2 |
Mapped gene | LOC105369822 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105369822 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10748128-T |
SNPs | rs10748128 |
Merged | 0 |
SNP id current | 10748128 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.352 |
P value | 4E-29 |
Pvalue mlog | 28.397940008672 |
P value text | |
Or beta | 0.038 |
%95 Ci | [0.032-0.044] unit increase |
Platform | Affymetrix, Illumina, Perlegen [2550858] (imputed) |
CNV | N |
Mapped trait | body height |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004339 |
Study accession | GCST002647 |