SNP Detail For rs10740455
1.Mapping Information
Human SNP ID rs10740455
Human chromosome chr10
Human SNP position 76151274
Pig chromosome chr14
Pig SNP position 84761251
2.Annotation Information
PubMed ID19901119
JournalJ Clin Oncol
Linkwww.ncbi.nlm.nih.gov/pubmed/19901119
StudyGermline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects.
Disease/TraitMethotrexate phramacokinetics (acute lymphoblastic leukemia)
Initial sample315 European ancestry cases, 73 African American cases, 5 Asian ancestry cases, 247 cases
Replication sampleNA
Region10q22.3
Chromosome idchr10
Chromosome position76151274
Reported geneC10orf11
Mapped geneC10orf11
Upstream gene id
Downstream gene id
SNP gene ids83938
Upstream gene distance
Downstream gene distance
SNP risk allelers10740455-A
SNPsrs10740455
Merged0
SNP id current10740455
Contextintron_variant
Intergenic0
Allele frequency0.08
P value0.000007
Pvalue mlog5.15490195998574
P value text
Or beta
%95 Ci[NR]
PlatformAffymetrix [398699]
CNVN
Mapped traitresponse to antineoplastic agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097327
Study accessionGCST000523