Human SNP ID | rs10740455 |
---|---|
Human chromosome | chr10 |
Human SNP position | 76151274 |
Pig chromosome | chr14 |
Pig SNP position | 84761251 |
PubMed ID | 19901119 |
---|---|
Journal | J Clin Oncol |
Link | www.ncbi.nlm.nih.gov/pubmed/19901119 |
Study | Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. |
Disease/Trait | Methotrexate phramacokinetics (acute lymphoblastic leukemia) |
Initial sample | 315 European ancestry cases, 73 African American cases, 5 Asian ancestry cases, 247 cases |
Replication sample | NA |
Region | 10q22.3 |
Chromosome id | chr10 |
Chromosome position | 76151274 |
Reported gene | C10orf11 |
Mapped gene | C10orf11 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 83938 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10740455-A |
SNPs | rs10740455 |
Merged | 0 |
SNP id current | 10740455 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.08 |
P value | 0.000007 |
Pvalue mlog | 5.15490195998574 |
P value text | |
Or beta | |
%95 Ci | [NR] |
Platform | Affymetrix [398699] |
CNV | N |
Mapped trait | response to antineoplastic agent |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0097327 |
Study accession | GCST000523 |