SNP Detail For rs10520789
1.Mapping Information
Human SNP ID rs10520789
Human chromosome chr15
Human SNP position 95598638
Pig chromosome chr7
Pig SNP position 89755405
2.Annotation Information
PubMed ID22569225
JournalPharmacogenet Genomics
Linkwww.ncbi.nlm.nih.gov/pubmed/22569225
StudyInvestigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis.
Disease/TraitResponse to TNF-alpha inhibitors in rheumatoid arthritis
Initial sample196 European ancestry cases
Replication sampleNA
Region15q26.2
Chromosome idchr15
Chromosome position95598638
Reported geneNR2F2
Mapped geneLOC105370995 - LOC105370996
Upstream gene id105370995
Downstream gene id105370996
SNP gene ids
Upstream gene distance6552
Downstream gene distance11371
SNP risk allelers10520789-?
SNPsrs10520789
Merged0
SNP id current10520789
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.0000006
Pvalue mlog6.22184874961635
P value text(Change in DAS28)
Or beta
%95 Ci
PlatformIllumina [486450]
CNVN
Mapped traitrheumatoid arthritis, response to TNF antagonist
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0004653
Study accessionGCST001510