SNP Detail For rs10518159
1.Mapping Information
Human SNP ID rs10518159
Human chromosome chr4
Human SNP position 76842845
Pig chromosome chr13
Pig SNP position 196252453
2.Annotation Information
PubMed ID21844884
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/21844884
StudyGenome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations
Disease/TraitResponse to platinum-based chemotherapy (cisplatin)
Initial sample176 Sub-Saharan African ancestry lymphoblastoid cell lines, 83 African ancestry lymphoblastoid cell lines, 175 East Asian ancestry lymphoblastoid cell lines, 174 European ancestry lymphoblastoid cell lines
Replication sampleNA
Region4q21.1
Chromosome idchr4
Chromosome position76842845
Reported geneintergenic
Mapped geneLOC105377289 - SOWAHB
Upstream gene id105377289
Downstream gene id345079
SNP gene ids
Upstream gene distance40321
Downstream gene distance52084
SNP risk allelers10518159-?
SNPsrs10518159
Merged0
SNP id current10518159
Contextintergenic_variant
Intergenic1
Allele frequency
P value0.000001
Pvalue mlog6
P value text
Or beta
%95 Ci
PlatformNR [~ 3000000] (imputed)
CNVN
Mapped traitresponse to cisplatin
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0072718
Study accessionGCST001201