SNP Detail For rs10516809
1.Mapping Information
Human SNP ID rs10516809
Human chromosome chr4
Human SNP position 88499935
Pig chromosome chr8
Pig SNP position 139962407
2.Annotation Information
PubMed ID22424883
JournalJ Allergy Clin Immunol
Linkwww.ncbi.nlm.nih.gov/pubmed/22424883
StudyGenome-wide association study of lung function decline in adults with and without asthma.
Disease/TraitPulmonary function decline
Initial sample1,441 European ancestry asthma cases, 2,677 European ancestry controls
Replication sample1,160 European ancestry asthma cases, 10,858 European ancestry controls
Region4q22.1
Chromosome idchr4
Chromosome position88499935
Reported geneHERC5
Mapped geneHERC5
Upstream gene id
Downstream gene id
SNP gene ids51191
Upstream gene distance
Downstream gene distance
SNP risk allelers10516809-?
SNPsrs10516809
Merged0
SNP id current10516809
Contextsynonymous_variant
Intergenic0
Allele frequencyNR
P value0.000009
Pvalue mlog5.04575749056067
P value text(FEV1 decline in asthmatics)
Or beta0.3063
%95 Ci[0.17-0.44] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitforced expiratory volume
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314
Study accessionGCST001444