Human SNP ID | rs10516173 |
---|---|
Human chromosome | chr4 |
Human SNP position | 5151418 |
Pig chromosome | chr8 |
Pig SNP position | 4964071 |
PubMed ID | 25461247 |
---|---|
Journal | Pharmacogenet Genomics |
Link | www.ncbi.nlm.nih.gov/pubmed/25461247 |
Study | Genome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols. |
Disease/Trait | Response to abacavir-containing treatment in HIV-1 infection (virologic failure) |
Initial sample | Up 346 European ancestry individuals, Up to 265 Black individuals, Up to 175 Hispanic individuals |
Replication sample | NA |
Region | 4p16.2 |
Chromosome id | chr4 |
Chromosome position | 5151418 |
Reported gene | NR |
Mapped gene | STK32B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 55351 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10516173-T |
SNPs | rs10516173 |
Merged | 0 |
SNP id current | 10516173 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.000005 |
Pvalue mlog | 5.30102999566398 |
P value text | (phenotype 2) |
Or beta | 2.85 |
%95 Ci | [NR] |
Platform | Illumina [> 8000000] (imputed) |
CNV | N |
Mapped trait | HIV-1 infection, virologic response measurement, response to abacavir |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0006906, http://www.ebi.ac.uk/efo/EFO_0006905 |
Study accession | GCST002769 |