SNP Detail For rs10511052
1.Mapping Information
Human SNP ID rs10511052
Human chromosome chr3
Human SNP position 76676752
Pig chromosome chr13
Pig SNP position 188476231
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region3p12.3
Chromosome idchr3
Chromosome position76676752
Reported geneNR
Mapped geneROBO2
Upstream gene id
Downstream gene id
SNP gene ids6092
Upstream gene distance
Downstream gene distance
SNP risk allelers10511052-G
SNPsrs10511052
Merged0
SNP id current10511052
Contextintron_variant
Intergenic0
Allele frequency0.950688225100133
P value0.000006
Pvalue mlog5.22184874961635
P value text(IGP7)
Or beta0.3598
%95 Ci[0.2-0.52] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848