Human SNP ID | rs10510921 |
---|---|
Human chromosome | chr3 |
Human SNP position | 64926476 |
Pig chromosome | chr13 |
Pig SNP position | 51156717 |
PubMed ID | 25187353 |
---|---|
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/25187353 |
Study | Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. |
Disease/Trait | Clozapine-induced agranulocytosis |
Initial sample | 161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls |
Replication sample | NA |
Region | 3p14.1 |
Chromosome id | chr3 |
Chromosome position | 64926476 |
Reported gene | ADAMTS9-AS2, MIR548A2 |
Mapped gene | LOC105377124, ADAMTS9-AS2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105377124, 100507098 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10510921-G |
SNPs | rs10510921 |
Merged | 0 |
SNP id current | 10510921 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.02 |
P value | 0.000007 |
Pvalue mlog | 5.15490195998574 |
P value text | |
Or beta | 3.52 |
%95 Ci | [2.97-4.07] |
Platform | Illumina [8809853] (imputed) |
CNV | N |
Mapped trait | drug-induced agranulocytosis, response to clozapine |
Mapped trait URI | http://purl.obolibrary.org/obo/HP_0012235, http://purl.obolibrary.org/obo/GO_0097338 |
Study accession | GCST002595 |