SNP Detail For rs10510921
1.Mapping Information
Human SNP ID rs10510921
Human chromosome chr3
Human SNP position 64926476
Pig chromosome chr13
Pig SNP position 51156717
2.Annotation Information
PubMed ID25187353
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25187353
StudyClozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.
Disease/TraitClozapine-induced agranulocytosis
Initial sample161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls
Replication sampleNA
Region3p14.1
Chromosome idchr3
Chromosome position64926476
Reported geneADAMTS9-AS2, MIR548A2
Mapped geneLOC105377124, ADAMTS9-AS2
Upstream gene id
Downstream gene id
SNP gene ids105377124, 100507098
Upstream gene distance
Downstream gene distance
SNP risk allelers10510921-G
SNPsrs10510921
Merged0
SNP id current10510921
Contextintron_variant
Intergenic0
Allele frequency0.02
P value0.000007
Pvalue mlog5.15490195998574
P value text
Or beta3.52
%95 Ci[2.97-4.07]
PlatformIllumina [8809853] (imputed)
CNVN
Mapped traitdrug-induced agranulocytosis, response to clozapine
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0012235, http://purl.obolibrary.org/obo/GO_0097338
Study accessionGCST002595