Human SNP ID | rs10484358 |
---|---|
Human chromosome | chr6 |
Human SNP position | 16255812 |
Pig chromosome | chr7 |
Pig SNP position | 12864427 |
PubMed ID | 23377640 |
---|---|
Journal | Am J Psychiatry |
Link | www.ncbi.nlm.nih.gov/pubmed/23377640 |
Study | Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. |
Disease/Trait | Major depressive disorder |
Initial sample | Up to 2,256 European ancestry cases |
Replication sample | NA |
Region | 6p22.3 |
Chromosome id | chr6 |
Chromosome position | 16255812 |
Reported gene | MYLIP, GMPR, ATXN1 |
Mapped gene | GMPR |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2766 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10484358-T |
SNPs | rs10484358 |
Merged | 0 |
SNP id current | 10484358 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.0827112 |
P value | 0.000001 |
Pvalue mlog | 6 |
P value text | (% improvement - SSRI treated - 2 weeks) |
Or beta | 0.4258 |
%95 Ci | [0.25-0.6] unit decrease |
Platform | Affymetrix, Illumina [1200000] (imputed) |
CNV | N |
Mapped trait | unipolar depression |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003761 |
Study accession | GCST001850 |