SNP Detail For rs10484358
1.Mapping Information
Human SNP ID rs10484358
Human chromosome chr6
Human SNP position 16255812
Pig chromosome chr7
Pig SNP position 12864427
2.Annotation Information
PubMed ID23377640
JournalAm J Psychiatry
Linkwww.ncbi.nlm.nih.gov/pubmed/23377640
StudyCommon genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.
Disease/TraitMajor depressive disorder
Initial sampleUp to 2,256 European ancestry cases
Replication sampleNA
Region6p22.3
Chromosome idchr6
Chromosome position16255812
Reported geneMYLIP, GMPR, ATXN1
Mapped geneGMPR
Upstream gene id
Downstream gene id
SNP gene ids2766
Upstream gene distance
Downstream gene distance
SNP risk allelers10484358-T
SNPsrs10484358
Merged0
SNP id current10484358
Contextintron_variant
Intergenic0
Allele frequency0.0827112
P value0.000001
Pvalue mlog6
P value text(% improvement - SSRI treated - 2 weeks)
Or beta0.4258
%95 Ci[0.25-0.6] unit decrease
PlatformAffymetrix, Illumina [1200000] (imputed)
CNVN
Mapped traitunipolar depression
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003761
Study accessionGCST001850