SNP Detail For rs10474352
1.Mapping Information
Human SNP ID rs10474352
Human chromosome chr5
Human SNP position 91436408
Pig chromosome chr2
Pig SNP position 101627104
2.Annotation Information
PubMed ID25038754
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25038754
StudyGenome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.
Disease/TraitBreast cancer
Initial sample2,867 Chinese ancestry cases, 2,285 Chinese ancestry controls, 2,246 Korean ancestry cases, 2,052 Korean ancestry controls
Replication sample5,029 Chinese ancestry cases, 5,302 Chinese ancestry controls, 6,066 Korean ancestry cases, 8,003 Korean ancestry controls, 6,572 Japanese ancestry cases, 6,539 Japanese ancestry controls, 16,003 European ancestry cases, 41,335 European ancestry controls
Region5q14.3
Chromosome idchr5
Chromosome position91436408
Reported geneARRDC3
Mapped geneARRDC3-AS1 - LOC105379078
Upstream gene id100129716
Downstream gene id105379078
SNP gene ids
Upstream gene distance15693
Downstream gene distance251068
SNP risk allelers10474352-C
SNPsrs10474352
Merged0
SNP id current10474352
Contextintron_variant
Intergenic1
Allele frequency0.482
P value0.000000002
Pvalue mlog8.69897000433601
P value text(East Asian)
Or beta1.09
%95 Ci[1.06-1.12]
PlatformAffymetrix [up to 1930412] (imputed)
CNVN
Mapped traitbreast carcinoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000305
Study accessionGCST002537