SNP Detail For rs10464366
1.Mapping Information
Human SNP ID rs10464366
Human chromosome chr7
Human SNP position 39081900
Pig chromosome chr18
Pig SNP position 60409186
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region7p14.1
Chromosome idchr7
Chromosome position39081900
Reported geneNR
Mapped genePOU6F2
Upstream gene id
Downstream gene id
SNP gene ids11281
Upstream gene distance
Downstream gene distance
SNP risk allelers10464366-T
SNPsrs10464366
Merged0
SNP id current10464366
Contextintron_variant
Intergenic0
Allele frequency0.23005360311804
P value0.000003
Pvalue mlog5.52287874528033
P value text(IGP24)
Or beta0.1748
%95 Ci[0.1-0.25] unit decrease
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848