SNP Detail For rs10453441
1.Mapping Information
Human SNP ID rs10453441
Human chromosome chr22
Human SNP position 45967859
Pig chromosome chr5
Pig SNP position 703105
2.Annotation Information
PubMed ID25823570
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25823570
StudyIdentification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia.
Disease/TraitCorneal curvature
Initial sampleUp to 3,248 Japanese ancestry individuals
Replication sample6,234 East Asian ancestry individuals, 2,007 European ancestry individuals
Region22q13.31
Chromosome idchr22
Chromosome position45967859
Reported geneWNT7B
Mapped geneWNT7B
Upstream gene id
Downstream gene id
SNP gene ids7477
Upstream gene distance
Downstream gene distance
SNP risk allelers10453441-A
SNPsrs10453441
Merged0
SNP id current10453441
Contextintron_variant
Intergenic0
Allele frequency0.33
P value3E-40
Pvalue mlog39.5228787452803
P value text
Or beta0.051
%95 Ci[0.043-0.059] unit increase
PlatformIllumina [1773334] (imputed)
CNVN
Mapped traitcorneal topography
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004345
Study accessionGCST002834