Human SNP ID | rs10440635 |
---|---|
Human chromosome | chr5 |
Human SNP position | 40490688 |
Pig chromosome | chr16 |
Pig SNP position | 26778337 |
PubMed ID | 21743469 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21743469 |
Study | Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. |
Disease/Trait | Ankylosing spondylitis |
Initial sample | 3,023 European ancestry cases, 8,779 European ancestry controls |
Replication sample | 2,111 European ancestry cases, 4,483 European ancestry controls |
Region | 5p13.1 |
Chromosome id | chr5 |
Chromosome position | 40490688 |
Reported gene | PTGER4 |
Mapped gene | LOC105374736 - LOC105374737 |
Upstream gene id | 105374736 |
Downstream gene id | 105374737 |
SNP gene ids | |
Upstream gene distance | 144133 |
Downstream gene distance | 109192 |
SNP risk allele | rs10440635-A |
SNPs | rs10440635 |
Merged | 0 |
SNP id current | 10440635 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.6 |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Illumina [2223620] (imputed) |
CNV | N |
Mapped trait | ankylosing spondylitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003898 |
Study accession | GCST001149 |