SNP Detail For rs10260816
1.Mapping Information
Human SNP ID rs10260816
Human chromosome chr7
Human SNP position 45970501
Pig chromosome chr18
Pig SNP position 54830678
2.Annotation Information
PubMed ID26390057
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26390057
StudyTrans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
Disease/TraitPulse pressure
Initial sample31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals
Replication sample87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals and 16,328 South Asian ancestry individuals
Region7p12.3
Chromosome idchr7
Chromosome position45970501
Reported geneIGFBP3
Mapped geneLOC102723446
Upstream gene id
Downstream gene id
SNP gene ids102723446
Upstream gene distance
Downstream gene distance
SNP risk allelers10260816-C
SNPsrs10260816
Merged
SNP id current10260816
Contextintron_variant
Intergenic0
Allele frequency0.605855210263958
P value0.00000000000002
Pvalue mlog13.698970004336
P value text
Or beta0.31454498
%95 Ci[0.23-0.39] mmHg increase
PlatformAffymetrix, Illumina, Perlegen [~ 2100000] (imputed)
CNVN
Mapped traitpulse pressure measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005763
Study accessionGCST003274