SNP Detail For rs1023721
1.Mapping Information
Human SNP ID rs1023721
Human chromosome chr4
Human SNP position 21204867
Pig chromosome chr8
Pig SNP position 15942502
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region4p15.31
Chromosome idchr4
Chromosome position21204867
Reported geneNR
Mapped geneKCNIP4
Upstream gene id
Downstream gene id
SNP gene ids80333
Upstream gene distance
Downstream gene distance
SNP risk allelers1023721-T
SNPsrs1023721
Merged0
SNP id current1023721
Contextintron_variant
Intergenic0
Allele frequency0.941491348153093
P value0.000001
Pvalue mlog6
P value text(IGP45)
Or beta0.312
%95 Ci[0.19-0.44] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region4p15.31
Chromosome idchr4
Chromosome position21204867
Reported geneNR
Mapped geneKCNIP4
Upstream gene id
Downstream gene id
SNP gene ids80333
Upstream gene distance
Downstream gene distance
SNP risk allelers1023721-T
SNPsrs1023721
Merged0
SNP id current1023721
Contextintron_variant
Intergenic0
Allele frequency0.941465292386465
P value0.000001
Pvalue mlog6
P value text(IGP5)
Or beta0.3141
%95 Ci[0.19-0.44] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848