SNP Detail For rs10229583
1.Mapping Information
Human SNP ID rs10229583
Human chromosome chr7
Human SNP position 127606849
Pig chromosome chr18
Pig SNP position 21686214
2.Annotation Information
PubMed ID23532257
JournalDiabetologia
Linkwww.ncbi.nlm.nih.gov/pubmed/23532257
StudyGenome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4.
Disease/TraitType 2 diabetes
Initial sample684 Han Chinese ancestry cases, 955 Han Chinese ancestry controls
Replication sample18,954 East Asian ancestry cases, 18,029 East Asian ancestry controls, 794 Malay ancestry cases, 1,204 Malay ancestry controls, 977 Indian ancestry cases, 1,169 Indian ancestry controls, 8,130 European ancestry cases, 38,987 European ancestry controls
Region7q32.1
Chromosome idchr7
Chromosome position127606849
Reported geneARF5, PAX4, SND1
Mapped geneFSCN3 - PAX4
Upstream gene id29999
Downstream gene id5078
SNP gene ids
Upstream gene distance5052
Downstream gene distance3443
SNP risk allelers10229583-G
SNPsrs10229583
Merged0
SNP id current10229583
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.825
P value0.0000000002
Pvalue mlog9.69897000433601
P value text(East Asian)
Or beta1.14
%95 Ci[1.09-1.19]
PlatformIllumina [2925090] (imputed)
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST001919