Human SNP ID | rs10229583 |
---|---|
Human chromosome | chr7 |
Human SNP position | 127606849 |
Pig chromosome | chr18 |
Pig SNP position | 21686214 |
PubMed ID | 23532257 |
---|---|
Journal | Diabetologia |
Link | www.ncbi.nlm.nih.gov/pubmed/23532257 |
Study | Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4. |
Disease/Trait | Type 2 diabetes |
Initial sample | 684 Han Chinese ancestry cases, 955 Han Chinese ancestry controls |
Replication sample | 18,954 East Asian ancestry cases, 18,029 East Asian ancestry controls, 794 Malay ancestry cases, 1,204 Malay ancestry controls, 977 Indian ancestry cases, 1,169 Indian ancestry controls, 8,130 European ancestry cases, 38,987 European ancestry controls |
Region | 7q32.1 |
Chromosome id | chr7 |
Chromosome position | 127606849 |
Reported gene | ARF5, PAX4, SND1 |
Mapped gene | FSCN3 - PAX4 |
Upstream gene id | 29999 |
Downstream gene id | 5078 |
SNP gene ids | |
Upstream gene distance | 5052 |
Downstream gene distance | 3443 |
SNP risk allele | rs10229583-G |
SNPs | rs10229583 |
Merged | 0 |
SNP id current | 10229583 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.825 |
P value | 0.0000000002 |
Pvalue mlog | 9.69897000433601 |
P value text | (East Asian) |
Or beta | 1.14 |
%95 Ci | [1.09-1.19] |
Platform | Illumina [2925090] (imputed) |
CNV | N |
Mapped trait | type II diabetes mellitus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001360 |
Study accession | GCST001919 |