Human SNP ID | rs1021188 |
---|---|
Human chromosome | chr13 |
Human SNP position | 42541997 |
Pig chromosome | chr11 |
Pig SNP position | 25233730 |
PubMed ID | 21124946 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21124946 |
Study | Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone. |
Disease/Trait | Bone mineral density |
Initial sample | 1,934 European ancestry individuals |
Replication sample | Up to 3,835 European ancestry individuals |
Region | 13q14.11 |
Chromosome id | chr13 |
Chromosome position | 42541997 |
Reported gene | RANKL |
Mapped gene | LOC105370177 - TNFSF11 |
Upstream gene id | 105370177 |
Downstream gene id | 8600 |
SNP gene ids | |
Upstream gene distance | 56041 |
Downstream gene distance | 20739 |
SNP risk allele | rs1021188-C |
SNPs | rs1021188 |
Merged | 0 |
SNP id current | 1021188 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.18 |
P value | 0.00000000000002 |
Pvalue mlog | 13.698970004336 |
P value text | |
Or beta | 3.89 |
%95 Ci | [1.91-5.87] mg/cm3 decrease |
Platform | Illumina [2417199] (imputed) |
CNV | N |
Mapped trait | bone density |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003923 |
Study accession | GCST000877 |
PubMed ID | 23437003 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23437003 |
Study | Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure. |
Disease/Trait | Bone mineral density |
Initial sample | up to 5,878 European ancestry individuals |
Replication sample | up to 1,052 European ancestry individuals |
Region | 13q14.11 |
Chromosome id | chr13 |
Chromosome position | 42541997 |
Reported gene | TNFSF11 |
Mapped gene | LOC105370177 - TNFSF11 |
Upstream gene id | 105370177 |
Downstream gene id | 8600 |
SNP gene ids | |
Upstream gene distance | 56041 |
Downstream gene distance | 20739 |
SNP risk allele | rs1021188-C |
SNPs | rs1021188 |
Merged | 0 |
SNP id current | 1021188 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.17 |
P value | 0.00000000000004 |
Pvalue mlog | 13.397940008672 |
P value text | (Cortical vBMD) |
Or beta | 0.15 |
%95 Ci | [0.11-0.19] unit decrease |
Platform | Illumina [2401124] (imputed) |
CNV | N |
Mapped trait | bone density |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003923 |
Study accession | GCST001870 |