SNP Detail For rs10189905
1.Mapping Information
Human SNP ID rs10189905
Human chromosome chr2
Human SNP position 198814386
Pig chromosome chr15
Pig SNP position 113630991
2.Annotation Information
PubMed ID22144915
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22144915
StudyGenome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.
Disease/TraitCorneal astigmatism
Initial sample1,231 Chinese ancestry cases, 785 Chinese ancestry controls, 1,018 Malay ancestry cases, 1,220 Malay ancestry controls
Replication sample825 Indian ancestry cases, 1,314 Indian ancestry controls, 760 Chinese ancestry child cases, 169 Chinese ancestry child controls, 397 Chinese ancestry trios
Region2q33.1
Chromosome idchr2
Chromosome position198814386
Reported geneintergenic
Mapped geneLOC105373831 - SATB2
Upstream gene id105373831
Downstream gene id23314
SNP gene ids
Upstream gene distance42056
Downstream gene distance455114
SNP risk allelers10189905-?
SNPsrs10189905
Merged0
SNP id current10189905
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.0000006
Pvalue mlog6.22184874961635
P value text
Or beta1.32
%95 Ci[1.18-1.46]
PlatformIllumina [460528]
CNVN
Mapped traitAstigmatism
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0000483
Study accessionGCST001339