Human SNP ID | rs10189905 |
---|---|
Human chromosome | chr2 |
Human SNP position | 198814386 |
Pig chromosome | chr15 |
Pig SNP position | 113630991 |
PubMed ID | 22144915 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22144915 |
Study | Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism. |
Disease/Trait | Corneal astigmatism |
Initial sample | 1,231 Chinese ancestry cases, 785 Chinese ancestry controls, 1,018 Malay ancestry cases, 1,220 Malay ancestry controls |
Replication sample | 825 Indian ancestry cases, 1,314 Indian ancestry controls, 760 Chinese ancestry child cases, 169 Chinese ancestry child controls, 397 Chinese ancestry trios |
Region | 2q33.1 |
Chromosome id | chr2 |
Chromosome position | 198814386 |
Reported gene | intergenic |
Mapped gene | LOC105373831 - SATB2 |
Upstream gene id | 105373831 |
Downstream gene id | 23314 |
SNP gene ids | |
Upstream gene distance | 42056 |
Downstream gene distance | 455114 |
SNP risk allele | rs10189905-? |
SNPs | rs10189905 |
Merged | 0 |
SNP id current | 10189905 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.0000006 |
Pvalue mlog | 6.22184874961635 |
P value text | |
Or beta | 1.32 |
%95 Ci | [1.18-1.46] |
Platform | Illumina [460528] |
CNV | N |
Mapped trait | Astigmatism |
Mapped trait URI | http://purl.obolibrary.org/obo/HP_0000483 |
Study accession | GCST001339 |