Human SNP ID | rs10189761 |
---|---|
Human chromosome | chr2 |
Human SNP position | 646364 |
Pig chromosome | chr3 |
Pig SNP position | 141853449 |
PubMed ID | 23563607 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23563607 |
Study | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. |
Disease/Trait | Obesity |
Initial sample | 93,015 European ancestry overweight individuals, 32,858 European ancestry class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls |
Replication sample | 65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls |
Region | 2p25.3 |
Chromosome id | chr2 |
Chromosome position | 646364 |
Reported gene | TMEM18 |
Mapped gene | LOC105373353 - TMEM18 |
Upstream gene id | 105373353 |
Downstream gene id | 129787 |
SNP gene ids | |
Upstream gene distance | 266 |
Downstream gene distance | 21609 |
SNP risk allele | rs10189761-A |
SNPs | rs10189761 |
Merged | 0 |
SNP id current | 10189761 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.82 |
P value | 6E-24 |
Pvalue mlog | 23.2218487496163 |
P value text | (Obesity class II) |
Or beta | 1.24 |
%95 Ci | [NR] |
Platform | Affymetrix, Illumina [~ 2800000] (imputed) |
CNV | N |
Mapped trait | obesity |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001073 |
Study accession | GCST001953 |