SNP Detail For rs10128264
1.Mapping Information
Human SNP ID rs10128264
Human chromosome chr10
Human SNP position 79200216
Pig chromosome chr14
Pig SNP position 88194814
2.Annotation Information
PubMed ID24709693
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/24709693
StudyGenome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
Disease/TraitResponse to methotrexate in juvenile idiopathic arthritis
Initial sample694 European ancestry child cases
Replication sampleNA
Region10q22.3
Chromosome idchr10
Chromosome position79200216
Reported geneZMIZ1
Mapped geneZMIZ1
Upstream gene id
Downstream gene id
SNP gene ids57178
Upstream gene distance
Downstream gene distance
SNP risk allelers10128264-C
SNPsrs10128264
Merged0
SNP id current10128264
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000001
Pvalue mlog6
P value text(ParVAS)
Or beta1.18
%95 Ci[0.71-1.65] unit decrease
PlatformIllumina [586062]
CNVN
Mapped traitresponse to methotrexate, chronic childhood arthritis
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0031427, http://www.ebi.ac.uk/efo/EFO_0002609
Study accessionGCST002408