SNP Detail For rs10089517
1.Mapping Information
Human SNP ID rs10089517
Human chromosome chr8
Human SNP position 59266162
Pig chromosome chr4
Pig SNP position 80455933
2.Annotation Information
PubMed ID22589738
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22589738
StudyGenome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
Disease/TraitVisceral adipose tissue/subcutaneous adipose tissue ratio
Initial sample5,560 European ancestry female individuals, 4,997 European ancestry male individuals
Replication sampleNA
Region8q12.1
Chromosome idchr8
Chromosome position59266162
Reported geneTOX
Mapped geneLOC100505501 - NUDT15P1
Upstream gene id100505501
Downstream gene id574532
SNP gene ids
Upstream gene distance144815
Downstream gene distance290537
SNP risk allelers10089517-C
SNPsrs10089517
Merged0
SNP id current10089517
Contextintergenic_variant
Intergenic1
Allele frequency0.71
P value0.000002
Pvalue mlog5.69897000433601
P value text(overall)
Or beta
%95 Ci
PlatformAffymetrix, Illumina [2500000] (imputed)
CNVN
Mapped traitvisceral:subcutaneous adipose tissue ratio
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004767
Study accessionGCST001524
PubMed ID25233373
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/25233373
StudyGenome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 Loci.
Disease/TraitHyperopia
Initial sample7,068 European ancestry cases, 6,844 European ancestry controls
Replication sample1,554 European ancestry cases, 892 cases, 1,654 European ancestry controls, 2,921 controls
Region8q12.1
Chromosome idchr8
Chromosome position59266162
Reported geneTOX
Mapped geneLOC100505501 - NUDT15P1
Upstream gene id100505501
Downstream gene id574532
SNP gene ids
Upstream gene distance144815
Downstream gene distance290537
SNP risk allelers10089517-?
SNPsrs10089517
Merged0
SNP id current10089517
Contextintergenic_variant
Intergenic1
Allele frequency
P value0.00000000002
Pvalue mlog10.698970004336
P value text
Or beta
%95 Ci
PlatformAffymetrix, Illumina [up to 3397980] (imputed)
CNVN
Mapped traithypermetropia
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0000540
Study accessionGCST002617