Human SNP ID | rs10084630 |
---|---|
Human chromosome | chr22 |
Human SNP position | 37283446 |
Pig chromosome | chr5 |
Pig SNP position | 8103631 |
PubMed ID | 24709693 |
---|---|
Journal | Pharmacogenomics J |
Link | www.ncbi.nlm.nih.gov/pubmed/24709693 |
Study | Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases. |
Disease/Trait | Response to methotrexate in juvenile idiopathic arthritis |
Initial sample | 694 European ancestry child cases |
Replication sample | NA |
Region | 22q13.1 |
Chromosome id | chr22 |
Chromosome position | 37283446 |
Reported gene | C1QTNF6, RAC2, CYTH4, ELFN2 |
Mapped gene | CYTH4 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 27128 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10084630-G |
SNPs | rs10084630 |
Merged | 0 |
SNP id current | 10084630 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.000009 |
Pvalue mlog | 5.04575749056067 |
P value text | (ParVAS) |
Or beta | 1.13 |
%95 Ci | [0.64-1.62] unit increase |
Platform | Illumina [586062] |
CNV | N |
Mapped trait | response to methotrexate, chronic childhood arthritis |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0031427, http://www.ebi.ac.uk/efo/EFO_0002609 |
Study accession | GCST002408 |