SNP Detail For rs10084630
1.Mapping Information
Human SNP ID rs10084630
Human chromosome chr22
Human SNP position 37283446
Pig chromosome chr5
Pig SNP position 8103631
2.Annotation Information
PubMed ID24709693
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/24709693
StudyGenome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
Disease/TraitResponse to methotrexate in juvenile idiopathic arthritis
Initial sample694 European ancestry child cases
Replication sampleNA
Region22q13.1
Chromosome idchr22
Chromosome position37283446
Reported geneC1QTNF6, RAC2, CYTH4, ELFN2
Mapped geneCYTH4
Upstream gene id
Downstream gene id
SNP gene ids27128
Upstream gene distance
Downstream gene distance
SNP risk allelers10084630-G
SNPsrs10084630
Merged0
SNP id current10084630
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000009
Pvalue mlog5.04575749056067
P value text(ParVAS)
Or beta1.13
%95 Ci[0.64-1.62] unit increase
PlatformIllumina [586062]
CNVN
Mapped traitresponse to methotrexate, chronic childhood arthritis
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0031427, http://www.ebi.ac.uk/efo/EFO_0002609
Study accessionGCST002408