SNP Detail For rs10002492
1.Mapping Information
Human SNP ID rs10002492
Human chromosome chr4
Human SNP position 12578222
Pig chromosome JH118986-1
Pig SNP position 70750
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region4p15.33
Chromosome idchr4
Chromosome position12578222
Reported geneNR
Mapped geneLOC105374492
Upstream gene id
Downstream gene id
SNP gene ids105374492
Upstream gene distance
Downstream gene distance
SNP risk allelers10002492-G
SNPsrs10002492
Merged0
SNP id current10002492
Contextintergenic_variant
Intergenic0
Allele frequency0.167227182224207
P value0.000008
Pvalue mlog5.09691001300805
P value text(IGP23)
Or beta0.1837
%95 Ci[0.1-0.26] unit decrease
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848