P L E K                                   
predictor of long non-coding RNAs and messenger RNAs based on an improved k-mer scheme
PLEK
We present a tool called PLEK (predictor of long non-coding RNAs and messager RNAs based on k-mer scheme), which uses an improved computational pipeline based on k-mer and support vector machine (SVM) to distinguish long non-coding RNAs (lncRNAs) from messager RNAs (mRNAs).

PLEK.py -- used to differentiate lncRNAs from mRNAs.

PLEKModelling.py -- used to build your own classifier with your training data (mRNA/lncRNA transcripts).

Highlights
Users can used the default settings to run PLEK on vertebrate datasets.
Users can use the model we built on maize datasets to predict on other plants.
Users can build their own models to predict on non-vertebrates and others.
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Citation

Aimin Li,Junying Zhang and Zhongyin Zhou: PLEK: A tool for predicting long non-coding RNAs and messenger RNAs based on an improved k-mer scheme.  BMC bioinformatics 2014, 15:311.

Cited by (Google Scholar)



de Oliveira Júnior N G, da Rocha Fernandes G, Cardoso M H, et al. Venom gland transcriptome analyses of two freshwater stingrays (Myliobatiformes: Potamotrygonidae) from Brazil[J]. Scientific reports, 2016, 6.

Bakhtiarizadeh M R, Hosseinpour B, Arefnezhad B, et al. In silico prediction of long intergenic non-coding RNAs in sheep[J]. Genome, 2016, 59(4): 263-275.

Liu Y J, Zhang J Y, Li A M, et al. Detection of Piwi-interacting RNAs based on sequence features[J].Genetics and Molecular Research 15 (2): gmr.15028638.

de Castro M H, de Klerk D, Pienaar R, et al. De novo assembly and annotation of the salivary gland transcriptome of Rhipicephalus appendiculatus male and female ticks during blood feeding[J]. Ticks and Tick-borne Diseases, 2016.

Legeai F, Derrien T. Identification of long non-coding RNAs in insects genomes[J]. Current Opinion in Insect Science, 2015, 7: 37-44.

Achawanantakun R, Chen J, Sun Y, et al. LncRNA-ID: Long non-coding RNA IDentification using balanced random forests[J]. Bioinformatics, 2015, 31(24): 3897-3905.

Maag J L V, Panja D, Sporild I, et al. Dynamic expression of long noncoding RNAs and repeat elements in synaptic plasticity[J]. Frontiers in neuroscience, 2015, 9.

Housman G, Ulitsky I. Methods for distinguishing between protein-coding and long noncoding RNAs and the elusive biological purpose of translation of long noncoding RNAs[J]. bioRxiv, 2015: 017889.

Boerner S, McGinnis K M. Computational Analysis of LncRNA from cDNA Sequences[J]. Long Non-Coding RNAs: Methods and Protocols, 2016: 255-269.

CHEN Si-Tong, CEN Yi, LIU Jian-Fa, LI Yang, LIAO Qi. Bioinformatics methods of identifying and predicting long noncoding RNAs[J]. Chinese Bulletin of Life Sciences, 2015, 27(007): 946-952.

Quick Contact

Aimin Li
LiAiminMail@gmail.com
Junying Zhang
jyzhang@mail.xidian.edu.cn
About this website
This website provides guide and files related to PLEK.